A novel CD40 ligand mutation in a patient with pneumonia, neutropenia, and hyperimmunoglobulin M phenotype.
نویسندگان
چکیده
I Mohammadzadeh, L Shahbaznejad, N Wang, E Farhadi, A Aghamohammadi, L Hammarström, N Rezaei 1 Non-Communicable Pediatric Diseases Research Center, Babol University of Medical Sciences, Babol, Iran 2 Research Center for Immunode ciencies, Children’s Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran 3 Division of Clinical Immunology, Department of Laboratory Medicine, Karolinska Institute at the Karolinska University Hospital Huddinge, Stockholm, Sweden 4 Molecular Immunology Research Center, Tehran University of Medical Sciences, Tehran, Iran 5 Department of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
منابع مشابه
Hyper-IgM Immunodeficiency with Enamel Defects: a Case Report
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The CD40 ligand (CD40L) and CD40 are two molecules belonging to the TNF/TNF receptor superfamily, and their role in adaptive immune system has widely been explored. However, the wide range of expression of these molecules on hematopoietic as well as nonhematopoietic cells has revealed multiple functions of the CD40/CD40L interactions on different cell types and processes such as granulopoiesis....
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ورودعنوان ژورنال:
- Journal of investigational allergology & clinical immunology
دوره 23 1 شماره
صفحات -
تاریخ انتشار 2013